Southern Region or South Region may refer to:
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Southern Nigeria
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Southern Region (Boy Scouts of America)
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Southern Region, Bauchi, Nigeria
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South Region, Brazil, an official grouping of states for economic and statistical purposes
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Southern Region (Eritrea)
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Southern Region (Iceland)
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Southern Region, Ireland, statistical region
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Southern Region, Malawi
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Southern Region, Malta
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Southern Region, Serbia
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Southern Region of British Railways
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Southern Thailand, Thailand
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South Region (Cameroon)
See also
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Southern Chile (wine region)
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Central Region (disambiguation)
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Eastern Region (disambiguation)
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Northern Region (disambiguation)
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Western Region (disambiguation)